Chemistry thesis topics

  1. Potential radiopharmaceuticals labeled with α-emitter 227Th for targeted radionuclide therapy.
    • Supervisor: dr hab. Marek Pruszyński
    • Description: The aim of this dissertation will be to obtain potential radiopharmaceuticals labeled with 227Th for targeted radionuclide therapy. The PhD student will conduct research on the separation of 227Th from its parent radionuclide 227Ac, finding and selecting the best chelate ligand to stably bind 227Th to a suitable biomolecule (monoclonal antibody, its fragment or a simple peptide), followed by a series of biological studies on cells of the potential radiopharmaceutical candidate: receptor specificity and binding affinity, internalization, toxicity etc. Preliminary tests will also be carried out using other thorium radionuclides: 232Th and 226Th.
  2. Novel Metal-Organic Framework based materials for the sequestration of radioactive nuclides from the aqueous environment
    • Supervisor: Prof. dr hab. Zakrzewska-Kołtuniewicz
    • Auxiliary Supervisor: dr eng. Bożena Sartowska
    • Description: Metal-Organic Framework materials emerged as a new class of hybrid porous materials built up of metal (metal-oxide) clusters linked by polytypic organic linkers via coordinative bond. We are witnessing an extraordinary dynamic development in the field of MOF synthesis and applications in the last years, especially in the field of gas sorption and storage, separation of the gaseous mixtures, catalysis, drug encapsulation. The aim of the project is to develop novel MOF type sorbents for radioactive species sequestration from aqueous environment e.g. pertechnetate anion or uranyl anion.
    • Note: The works will be conducted in the cooperation with CSIRO (The Council for Scientific and Industrial Research, Pretoria, South Africa) in the frame of PET-MOF-CLEANWATER project funded by National Centre for Research and Development (Poland).
  3. Removal of SO2 and NOx emission from ship emission using electron beam–wet scrubber method
    • Supervisor: dr hab. Yongxia Sun
    • Description: SO2 and NOx’s emission from marine transportation sector causes a serious environmental problem, especially in emission control area (ECA). At present, there is no applicable technology to simultaneously remove SO2 and NOx from ship emission. Electron beam (EB) hybrid wet scrubber method has shown its positive effect on SO2 and NOx abatement. In this research work, the chemical mechanism of EB combined with wet scrubbers will be studied. Different parameters , such as oxidants, pH, gas/liquid ratio, irradiation dose etc., influencing on the removal efficiency of these two pollutants will be investigated, the scrubbing solution after process will be taken into consideration.
    • Note: This work will be partly financed by the TANGO2 project and H2020 Aries-proof of concept.